# US 2018/0321179 A1 · Methods and systems for hematocrit measurement > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2018/0321179 A1 - Document ID: US20180321179A1 - Status: Published application - Kind: A1 - Application number: 15/971,636 - Filed: 2018-05-04 - Published: 2018-11-08 - Earliest claimed: 2017-05-05 - Assignees: Trividia Health, Inc. - Applicants: Trividia Health, Inc. - Inventors: Steven V. Leone - Web page: https://patentgrep.com/patent/US20180321179A1 ## CPC - G01N 27/3274: {Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration (coding of calibration information G01N33/48771)} - C12Q 1/006: {for glucose} - G01N 27/3273: {Devices therefor, e.g. test element readers, circuitry (details not specific to biochemical electrodes G01N33/4875)} - G01N 33/66: involving blood sugars, e.g. galactose - G01N 33/80: involving blood groups or blood types {or red blood cells (white blood cells G01N33/56972)} - G01N 27/3272: {Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels (optical biosensors G01N33/52)} - G01N 33/49: Blood {(chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80)} - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - C12Q: MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES ## Abstract Systems and methods for hematocrit measurement are provided. In some embodiments, a method for measuring glucose in a blood sample comprises measuring hematocrit in a blood sample using a Thevenin equivalent circuit to calculate a hematocrit complex impedance value, mapping the calculated hematocrit impedance to a hematocrit concentration in the blood sample, and calculating a concentration of glucose in the blood sampled using the mapped hematocrit concentration. ## Claims ### Claim 1 A method for measuring glucose in a blood sample, comprising: measuring hematocrit in a blood sample using a Thevenin equivalent circuit to calculate a hematocrit complex impedance value; mapping the calculated hematocrit impedance to a hematocrit concentration in the blood sample; and calculating a concentration of glucose in the blood sampled using the mapped hematocrit concentration. ### Claim 2 (depends on 1) The method of claim 1, wherein measuring the hematocrit includes measuring a response current to an excitation voltage. ### Claim 3 (depends on 2) The method of claim 2, wherein the response current is inversely proportional to the hematocrit concentration in the blood sample. ### Claim 4 (depends on 2) The method of claim 2, wherein the response current is used to calculate the hematocrit complex impedance value. ### Claim 5 (depends on 1) The method of claim 1, wherein the calculating the concentration of glucose includes adjusting a measured glucose value using the mapped hematocrit concentration. ### Claim 6 (depends on 1) The method of claim 1, further comprising detecting the blood sample for analysis. ### Claim 7 (depends on 6) The method of claim 6, wherein an excitation signal is applied to the blood sample such that the response to the excitation signal is analyzed to determine a glucose concentration in the blood sample. ### Claim 8 (depends on 7) The method of claim 7, wherein the glucose value is dependent on the mapped hematocrit concentration. ### Claim 9 A system for diagnostic testing comprising: a test strip; and an electronic meter for performing a diagnostic test on a sample applied to the test strip inserted therein, the electronic meter comprising: a housing having a test port for receiving the test strip, and a processor programmed to perform the steps of: measuring hematocrit in the sample placed onto a test strip using a Thevenin equivalent circuit to calculate a hematocrit complex impedance value; and mapping the calculated hematocrit impedance to a hematocrit concentration in the blood sample; and calculating a concentration of glucose in the sample using the mapped hematocrit concentration. ### Claim 10 (depends on 9) The system of claim 9, wherein measuring the hematocrit includes measuring a response current to an excitation voltage. ### Claim 11 (depends on 10) The system of claim 10, wherein the response current is used to calculate the hematocrit complex impedance value. ### Claim 12 (depends on 9) The system of claim 9, wherein the calculating the concentration of glucose includes adjusting a measured glucose value using the mapped hematocrit concentration. ### Claim 13 (depends on 12) The system of claim 12, wherein an excitation signal is applied to the blood sample such that the response to the excitation signal is analyzed to determine a glucose concentration in the blood sample. ### Claim 14 (depends on 13) The system of claim 13, wherein the glucose concentration is dependent on the mapped hematocrit concentration. ### Claim 15 (depends on 9) The system of claim 9, wherein the processor is further programmed to detect when the sample is applied to the test strip. ### Claim 16 (depends on 12) The system of claim 12, wherein the processor is further programmed to display the adjusted glucose concentration. ### Claim 17 A method for measuring glucose in a blood sample, comprising: detecting a blood sample; measuring hematocrit in the blood sample placed onto a test strip using a Thevenin equivalent circuit to calculate a hematocrit complex impedance value; and mapping the calculated hematocrit impedance to a hematocrit concentration in the blood sample; applying an excitation signal to the blood sample such that the response to the excitation signal is analyzed to determine a glucose concentration in the blood sample; adjusting the glucose concentration in the blood sampled using the mapped hematocrit concentration; and displaying the adjusted glucose concentration. ### Claim 18 (depends on 17) The method of claim 17, wherein measuring the hematocrit includes measuring a response current to an excitation voltage. ### Claim 19 (depends on 18) The method of claim 18, wherein the response current is inversely proportional to the hematocrit concentration in the blood sample. ### Claim 20 (depends on 18) The method of claim 18, wherein the response current is used to calculate the hematocrit complex impedance value.