Agents and methods for treating and preventing seborrheic keratosis
AssigneeThe General Hospital Corporation
InventorsAnna I. Mandinova, Sam Lee, Victor A. Neel
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Abstract
Provided herein are methods and assays for isolating and culturing seborrheic keratosis cells ex vivo. Also provided herein are screening assays using cultured seborrheic keratosis cells and methods for treating seborrheic keratosis in a subject.
Claims9
A method for inducing apoptosis in a seborrheic keratosis cell, the method comprising contacting a seborrheic keratosis cell with an effective amount of a composition that inhibits Akt signaling, thereby inducing apoptosis in the cell.
A method for treating a seborrheic keratosis in a subject, the method comprising administering a composition comprising a therapeutically effective amount of an siRNA that targets Akt to a subject having seborrheic keratosis.
Dependencies are inferred from the claim text.