Back to results
US 2018/0319829 A1Published application
Phosphinic peptide derivatives for use as mmp-12 inhibitors
AssigneeDsm IP Assets B.V.
InventorsStéphanie BOUDON, Eileen JACKSON, Rolf SCHUETZ, Jürgen Herbert VOLLHARDT, Peter WIKSTROEM, Eliane Ursula WANDELER
Life of this patent
Estimating the term…
Abstract
This invention relates to compounds that are selective inhibitors of Matrix Metalloprotease-12 (MMP-12), to cosmetic and pharmaceutical compositions containing them, and to their use in the prevention and/or treatment of ailments associated with MMP-12. Formula (I).
Claims15
A compound of formula (I)
- wherein n is 0, 1 or 2,
- R1 is H, or an amino acid side chain which, if a functional group is present, may optionally be substituted by a C1-C6alkyl group, a C1-C6alkylcarbonyl group or a C1-C6alkoxycarbonyl group,
- R2 is H or Methyl, and
- R3 is selected from the group consisting of H, a C1-C6alkyl group and an arylC1-C6alkanyl group
- or a cosmetically acceptable salt thereof.
2 more elements
Dependencies are inferred from the claim text.