Filtration device for assays

A device for analyzing a biological fluid sample comprising:

• a porous material configured to receive and filter the biological fluid resulting in a filtrate comprising a first target analyte, wherein the porous material comprises a membrane filter;
• dried reagents comprising functionalized magnetic particles that react with the first target analyte,
• wherein the resulting filtrate rehydrates the dry reagents allowing the magnetic particles to react with the first analyte;
• an exposed surface of an integrated circuit having a sensor area, wherein the sensor area of the surface is functionalized to react with the first target analyte;
• and
• a capillary that delivers filtrate to the surface of the integrated circuit;
• wherein the integrated circuit comprises integrated conductors and integrated sensors, and
• wherein sensors integrated in the integrated circuit are used to detect specifically bound magnetic particles without necessitating another detecting device.