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US 2018/0291404 A1Published application
Eukaryotic cell with increased production of fermentation product
AssigneeDsm IP Assets B.V.
InventorsIoannis PAPAPETRIDIS, Jacobus THomas PRONK, Antonius Jeroen Adriaan VAN MARIS, Paul KLAASSEN
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Abstract
The present invention relates to a eukaryotic cell that is genetically modified comprising one or more heterologous gene encoding: a) D-glucose-6-phosphate dehydrogenase and/or b) 6-phosphogluconate dehydrogenase; and/or c) glucose dehydrogenase, gluconolactonase and gluconate kinase, wherein a), b) and glucose dehydrogenase in c) are NAD+ dependent.
Claims29
A eukaryotic cell that is genetically modified, comprising one or more heterologous gene encoding:
- a) D-glucose-6-phosphate dehydrogenase and/or
- b) 6-phosphogluconate dehydrogenase;
- and/or
- c) glucose dehydrogenase, gluconolactonase and gluconate kinase,
- wherein a), b) and glucose dehydrogenase in c) are NAD+ dependent.
2 more elements
Dependencies are inferred from the claim text.