System for unlocking a device from a guide wire

A guidewire stop configured to lock a medical device onto a guidewire, said guidewire stop comprising a locking element, an actuator coupled to the locking element and a locking tube and wherein at least a section of the guidewire and at least part of the locking element or actuator pass through the locking tube;

• characterized by an unlocking element configured to unlock the medical device from the guidewire,
• wherein the locking tube comprises the unlocking element;
• and
• wherein the guidewire stop has at least the following three configurations:
• an initial unlocked configuration in which the guidewire stop and the medical device are movable relative to the guidewire;
• a first locked configuration in which the guidewire stop and the medical device are not movable relative to the guidewire;
• and
• a first unlocked configuration in which the guidewire stop and the medical device are movable relative to the guidewire.

A method of replacing a first medical device with a second medical device, wherein the first medical device is locked onto a guidewire at a treatment site by a first guidewire stop comprising a first locking element, a first actuator coupled to the first locking element and a first locking tube, wherein the first locking tube comprises a first unlocking element, said method comprising:

• coupling the locking element with the unlocking element, thereby unlocking the first medical device from the guidewire;
• removing the first medical device from the treatment site along the guidewire;
• introducing the second medical device along the guidewire into the treatment site;
• locking the second medical device onto the guidewire by a second guidewire stop comprising second locking element, a second actuator coupled to the second locking element and a second locking tube, wherein the second locking tube comprises a second unlocking element;
• and
• when the medical procedure is concluded, coupling the second locking element with the second unlocking element, thereby unlocking the second medical device form the guidewire;
• and
• removing the second medical device from the treatment site along the guidewire.