Endo-cameral closure device
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human
InventorsToby Rogers, Merdim Sonmez, Ozgur Kocaturk, Robert J. Lederman
Life of this patent
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Abstract
Disclosed herein are devices and methods for closing a hole in the wall of a cardiovascular structure from the inside using a self-assembling closure device. The closure device can be delivered to the subject hole from the inside of the cardiovascular chamber using a transcatheter approach. Disclosed techniques involve deploying the closure device from the delivery device such that an endo-cameral portion of the closure device self-expands first to cover the hole from the inside, and then extra-cameral arms of the device are released to self-deploy against the outside of the wall by withdrawal of a retaining element, such as a guidewire, to secure the closure device to the wall.
Claims35
A device for closing a hole in a wall of a cardiovascular structure, comprising:
- an endo-cameral occlusion member configured to seal against an inner surface of a wall of a cardiovascular structure around a hole in the wall, the occlusion member comprising a resiliently deformable material and configured to be radially compressed to a delivery configuration for transcatheter delivery to within the cardiovascular structure adjacent the hole and configured to radially self-expand to a deployment configuration when released from within a delivery sheath;
- and
- first and second extra-cameral arms coupled to the occlusion member and configured to engage an outer surface of the wall in a deployed configuration to secure the device to the wall, the arms each comprising a base end portion coupled to the occlusion member, an engagement end portion configured to contact the outer surface of the wall when deployed, and an opening that receives a retaining element that retains the arms in a radially compressed delivery configuration, wherein the arms comprise a resiliently deformable material and are configured to be held in the radially compressed delivery configuration during transcatheter delivery and during deployment of the occlusion member, and wherein the arms are configured to resiliently self-expand to a deployment configuration after the occlusion member has self-expanded to its deployment configuration when the retaining element is removed from within the openings in the arms.
A method of closing a hole in a wall of a cardiovascular structure, comprising:
- advancing a delivery device through the a patient's anatomy to position a distal end portion of the delivery device extending through a hole in a wall of a cardiovascular structure, the delivery device carrying a closure member in a radially compress state within a sheath;
- retracting the sheath proximally to uncover the closure device and thereby allowing an endo-cameral occlusion member of the closure device to radially self-expand within the cardiovascular chamber while extra-cameral arms of the closure device remain in a radially compressed state positioned outside of the hole;
- positioning the expanded occlusion member against or adjacent to an inner surface of the wall covering the hole in the wall;
- and
- retracting a retaining element of the delivery device proximally from engagement with the extra-cameral arms to allow the arms the curl or bend radially outwardly and toward the occlusion member such that engagement end portions of the arms contact an outer surface of the wall and pinch the wall between the arms and the expanded occlusion member.
A device for closing a hole in a wall of a cardiovascular structure, comprising:
- an endo-cameral occlusion member configured to seal against an inner surface of a wall of a cardiovascular structure around a hole in the wall, the occlusion member comprising a resiliently deformable material and configured to be radially compressed to a delivery configuration for transcatheter delivery to within the cardiovascular structure adjacent the hole and configured to radially self-expand to a deployment configuration when released from within a delivery sheath;
- and
- an extra-cameral member coupled to the occlusion member and configured to engage an outer surface of the wall in a deployed configuration to secure the device to the wall, the extra-cameral member coupled to the occlusion member, the extra-cameral member configured to contact the outer surface of the wall when deployed, wherein the extra-cameral member comprises openings configured to receive a retaining element that retains the extra-cameral member in a radially compressed delivery configuration, wherein the extra-cameral member comprises a resiliently deformable material and is configured to be held in the radially compressed delivery configuration during transcatheter delivery and during deployment of the endo-cameral occlusion member, and wherein the extra-cameral member is configured to resiliently self-expand to a disk-shaped deployment configuration after the endo-cameral occlusion member has self-expanded to its deployment configuration when the retaining element is removed from within the openings in the extra-cameral member.
Dependencies are inferred from the claim text.