Combinational Therapy for Synergistic Inhibition of Gram-Positive and Gram-Negative Bacteria
AssigneeThe Governors of the University of Alberta
InventorsByeonghwa JEON, Jong-Chul KIM
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Abstract
Compositions and methods for inhibiting the growth of Gram-negative and/or Gram-positive bacteria and pharmaceutical compositions for treating infections of such bacteria in humans and animals are provided. An exemplary method for inhibiting the growth of Gram-negative and/or Gram-positive bacteria includes contacting the bacteria or an environment containing the bacteria with a combination of bacitracin and a gallate ester. An exemplary pharmaceutical composition includes bacitracin and a gallate ester.
Claims26
A method for inhibiting the growth of Gram-negative and/or Gram-positive bacteria which comprises contacting the bacteria or an environment containing the bacteria with a combination of bacitracin and a gallate ester.
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10-11. (canceled)
15-16. (canceled)
A method of treating a bacterial infection in an individual in need of such treatment which comprises administering to the individual a combined effective amount of bacitracin and a gallate ester.
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A pharmaceutical composition which comprises bacitracin and a gallate ester.
Dependencies are inferred from the claim text.