Salmon gill poxvirus
AssigneeVeterinæRinstituttet
InventorsMona Cecilie GJESSING, Torstein TENGS
Life of this patent
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Abstract
The present document is directed to a new poxvirus infecting salmon. The present document further discloses the genomic sequence of this double-stranded DNA virus and the use of this sequence information for detection, diagnosis and/or vaccine development for the virus.
Claims21
Piscine poxvirus characterized in that it comprises a nucleic acid sequence according to SEQ ID NO:1 or a nucleic acid sequence having at least 85% identity thereto, and/or a nucleic acid sequence complementary thereto.
An isolated nucleic acid molecule comprising or consisting of a nucleic acid sequence according to SEQ ID NO:1-9 or a variant thereof having at least 85% identity thereto, and/or a nucleic acid sequence complementary to said nucleic acid sequence or variant thereof.
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13-16. (canceled)
A method for detecting a Piscine poxvirus, in a sample, such as a tissue sample from fish, said method comprising detecting at least 5 consecutive nucleic acid bases of a nucleic acid sequence according to any one of SEQ ID NO:1-9, or a variant having at least 85% identity thereto, or a sequence complementary thereto.
An ex vivo method for detecting the presence of a Piscine poxvirus specific nucleic acid, a Piscine poxvirus specific polypeptides or proteins, and/or Piscine poxvirus, and/or diagnosing a Piscine poxvirus infection in a sample, said method comprising the steps of:
- a) contacting the sample with a nucleic acid fragment comprising or consisting of at least 5 contiguous nucleic acid bases of a nucleic acid molecule selected from the group consisting of SEQ ID NOs:
- 1-9, and/or an antibody that specifically binds to a peptide selected from the group consisting of SEQ ID NOs:10-15;
- b) detecting the formation of a complex between a Piscine poxvirus specific nucleic acid or polypeptide, respectively, and said nucleic acid fragment or antibody, respectively;
- wherein the presence of a complex indicates the presence of a Piscine poxvirus specific nucleic acid, a Piscine poxvirus specific polypeptide or protein, and/or Piscine poxvirus, and/or a Piscine poxvirus infection in said sample.
21-26. (canceled)
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Dependencies are inferred from the claim text.