Anti-ox40 antibodies and diagnostic uses thereof
AssigneeSpring BioScience Corporation
InventorsYifei Zhu, Zhiming Liao, Robert Pytela
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Abstract
The invention provides antibodies immunoreactive with human OX40 and methods of using the same. The antibodies are reactive with a portion of the C-terminus of the human OX40 protein that includes amino acids 266-277. The antibodies are useful for detecting OX40 protein expression in human tissue samples, including by immunohistochemistry, immunofluorescence, or immunoblot.
Claims26
An isolated antibody capable of specifically binding to a C-terminal portion of OX40 comprising amino acids 266-277 of SEQ ID NO:
- 1.
The method of claim 30, wherein the sample is from a subject having or predisposed to cancer or autoimmune disease.
Dependencies are inferred from the claim text.