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US 2018/0208655 A1Published application
Anti-gpnmb antibodies and diagnostic uses thereof
AssigneeSpring BioScience Corporation
InventorsYifei Zhu, Zhiming Liao, Fernando Jose Rebelo do Couto
Life of this patent
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Abstract
The present application discloses anti-GPNMB antibodies and methods of using the same. The antibodies are selected to bind to an epitope located in a C-terminal fragment of the protein and are selected for specificity in immunohistochemical assays. The antibodies are useful in, for example, immunohistochemical methods of detecting GPNMB-positive cells in tumors.
Claims29
An isolated antibody capable of specifically binding to a C-terminal portion of GPNMB comprising amino acids 22-486 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.