Compositions and Methods for Modulating Coagulation
AssigneeYale University
InventorsDemetrios BRADDOCK, Ronald ALBRIGHT
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Abstract
The present invention relates to compositions and methods for modulating coagulation through modulating the level or activity of NPP4.
Claims22
A method of treating Platelet Storage Pool Deficiency in a human subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an isolated soluble NPP4 polypeptide comprising amino acid residues 1-407 of SEQ ID NO:
- 1.
A method of treating Quebec Platelet disorder in a human subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an isolated soluble NPP4 polypeptide comprising amino acid residues 1-407 of SEQ ID NO:
- 1.
A method of treating Gray Platelet Syndrome in a human subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an isolated soluble NPP4 polypeptide comprising amino acid residues 1-407 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.