Methods and pharmaceutical compositions for the treatment of hepatitis b virus infection
AssigneesInserm (Institut National De La Sante Et De La Recherche Medicale), Universite Claude Bernard Lyon 1, Ens-Ecole Normale Superieure De Lyon, Centre National de la Recherche Scientifique (CNRS), Edelris, Poxel
InventorsPATRICE ANDRE, VINCENT LOTTEAU, PAULINE RADREAU, MARINE GILARDONE, AMAURY PATIN, DIDIER ROCHE, DANIEL CRAVO, SOPHIE HALLAKOU-BOZEC
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Abstract
The present invention relates to methods and pharmaceutical compositions for the treatment of hepatitis B virus infection. In particular, the present invention relates to farnesoid X receptor (FXR) agonists for use in a method for the treatment of hepatitis B virus infection in a subject in need thereof.
Claims16
A method for treating a chronic hepatitis B virus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a farnesoid X receptor (FXR) agonist.
A method for reducing synthesis and/or secretion of HBsAg and/or HBeAG or for reducing serum HBV DNA in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a farnesoid X receptor (FXR) agonist.
Dependencies are inferred from the claim text.