US 2018/0161417 A1Published application

Immortalized Porcine Alveolar Macrophage

AssigneeIntervet Inc.

InventorsJaap Kool, Carla Christina Schrier

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Abstract

The present invention relates to immortalized porcine alveolar macrophages (PAMs), to cell cultures comprising such PAMs, to methods for the immortalization of PAMs, to methods of replicating PRRS virus on immortalised PAMs and to methods for the preparation of vaccines comprising PRRSV.

Claims12

Dependent claims

An immortalized porcine alveolar macrophage (PAM), wherein the PAM is susceptible to Porcine Respiratory and Reproductive Virus (PRRSV), expresses an SV40 T antigen and does not comprise retroviral Long Terminal Repeat DNA capable of retroviral gene expression.

Dependencies are inferred from the claim text.

Facts

Application: 15/836,083Filed 8 Dec 2017
Priority: EP 13196834.912 Dec 2013
Published: 14 Jun 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification15 codes

A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens
A61P 31/12
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antivirals
C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
C12N 5/0645
Cells from the blood or the immune system: macrophages, e.g. Kuepfer cells in the liver; Monocytes

Family

Application15/102,971Division · filed 9 Jun 2016
Application15/836,083Division
US 10,166,282 B2Related patent
US 2016/0303220 A1Published application
US 9,872,896 B2Related patent
US 2018/0161417 A1This patent

From the US filing history. Foreign family members aren’t listed.

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