Diagnosis of chronic fatigue diseases using detection antibodies directed against a β-adrenergic receptor
AssigneesCelltrend GmbH, Charite-Universitatsmedizin Berlin
InventorsHarald HEIDECKE, Kai SCHULZE-FORSTER, Carmen SCHEIBENBOGEN
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Abstract
The application relates to a method for diagnosis of a chronic fatigue disease, e.g. CFS or CRF, comprising the step of determining the presence or absence of antibodies directed against β-adrenergic receptor in a sample of the subject to be diagnosed, wherein the presence of antibodies directed against β-adrenergic receptor is indicative of the chronic fatigue disease in said subject. Furthermore, the application relates to kits comprising β-adrenergic receptor or an antigenic peptide thereof and the use of β-adrenergic receptor or an antigenic peptide thereof for the diagnosis of a chronic fatigue disease.
Claims25
A method for diagnosis of a chronic fatigue disease in a subject, comprising
- determining the presence or absence of antibodies directed against one or more β-adrenergic receptor in a sample of the subject to be diagnosed,
- wherein the presence of antibodies directed against β-adrenergic receptor is indicative of the chronic fatigue disease in said subject.
A kit for diagnosing a chronic fatigue disease, said kit comprising a β-adrenergic receptor or an antigenic peptide thereof.
A product comprising a β-adrenergic receptor or an antigenic peptide thereof, or of a kit comprising said product for the diagnosis of a chronic fatigue disease.
A method for removal of β-adrenergic receptor antibodies from isolated blood, comprising:
- (i) determining in a sample of a subject the presence or absence of an β-adrenergic receptor antibodies is determined in a sample;
- and
- (ii) removing β-adrenergic receptor antibodies from isolated blood of the subject.
Dependencies are inferred from the claim text.