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US 2018/0155733 A1Published application
A method for producing resveratrol
OwnerErnesto SIMON VECILLA, Carlos Casado VAZQUEZ +1inventors
InventorsErnesto SIMON VECILLA, Carlos Casado VAZQUEZ, Niels Bjerg JENSEN
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Abstract
Recombinant hosts and methods for producing resveratrol in recombinant hosts are disclosed herein.
Claims41
A recombinant host comprising:
- (a) a gene encoding a 3-Deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase polypeptide;
- (b) a gene encoding a chorismate mutase polypeptide;
- and
- (c) a gene encoding an acetyl-CoA carboxylase polypeptide;
- wherein at least one of the genes is a recombinant gene,
- wherein the host is capable of producing a stilbene.
3 more elements
A method of producing a stilbene, comprising:
- (a) growing a recombinant host in a culture medium, under conditions in which the genes are expressed,
- wherein the host comprises:
- (i) a gene encoding a 3-Deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase polypeptide;
- (ii) a gene encoding a chorismate mutase polypeptide;
- and
- (iii) a gene encoding an acetyl-CoA carboxylase polypeptide;
- wherein at least one of the genes is a recombinant gene,
- and, optionally
- (b) recovering the stilbene from the culture media.
6 more elements
Dependencies are inferred from the claim text.