Corneal epithelioid cells derived from surface ectodermal cells
AssigneeOsaka University
InventorsKohji Nishida, Yuzuru SASAMOTO, Ryuhei HAYASHI
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Abstract
The present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell from a surface ectoderm-derived cell. More specifically, the present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell, comprising introducing PAX6, KLF4, and OCT4 into a surface ectoderm-derived cell, such as an oral mucosal epithelial cell, and a corneal epithelioid cell induced by the method.
Claims12
A method for producing a corneal epithelial cell, comprising introducing PAX6, KLF4, and OCT4 into a surface ectoderm-derived cell to induce a keratin 12-positive corneal epithelioid cell.
A keratin 12-positive corneal epithelioid cell directly induced from a surface ectoderm-derived cell.
Dependencies are inferred from the claim text.