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US 2018/0143189 A1Published application
Methods for isolating a target analyte from a heterogenous sample
AssigneeDNAE Group Holdings Limited
InventorsSergey A. Dryga, Victor C. Esch, Lisa-Jo Ann Clarizia, Eddie W. Adams, Thearith H. Ung, Ravil A. Sitdikov
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Abstract
The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.
Claims20
1-26. (canceled)
A method for isolating pathogen from a heterogeneous sample, the method comprising:
- providing a vessel that contains a heterogeneous sample, the vessel being coupled to a fluidic device that comprises a magnet;
- introducing to the vessel magnetic particles conjugated to pathogen-binding moieties;
- binding the magnetic particles to a pathogen in the heterogeneous sample;
- flowing the heterogeneous sample from the vessel through a channel in the fluidic device;
- and
- magnetically separating the pathogen in the sample by capturing the magnetic particles with the magnet.
3 more elements
Dependencies are inferred from the claim text.