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AssigneeSusavion Biosciences, Inc.
InventorsLaura L. Eggink, J. Kenneth Hoober
Estimating the term…
The methods and compounds disclosed herein are useful in treating a subject having cancer or a viral infection by modulating the innate and adaptive immune systems typically by both inhibiting the function of inhibitory receptors and enhancing activity of activating receptors. Preferred therapeutic compositions comprise a carrier; at least one agent selected from the group consisting of: an anti-inflammatory agent, a cytotoxic T cell proliferation agent, or a NK cell proliferation agent; and a therapeutic peptide of the invention. In certain embodiments the compositions further include a second therapeutic peptide and/or an immunoglobulin admixed therewith in an amount sufficient to enhance passive immunoprotection in the subject.
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A method of treating an immunocompromised subject, a subject having cancer and/or a subject having a viral infection:
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13-14. (canceled)
17-19. (canceled)
A therapeutic composition comprising a carrier, a therapeutic peptide or a multivalent structured polypeptide comprising multiple copies of the therapeutic peptide, wherein the therapeutic peptide is NQHTPR (SEQ ID NO:5), wherein the therapeutic peptide or multivalent structured polypeptide is in an amount sufficient to treat the cancer in a subject;
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Dependencies are inferred from the claim text.