Cell Penetrating Peptides and Complexes Comprising the Same
AssigneeAmal Therapeutics SA
InventorMadiha DEROUAZI
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Abstract
The present invention provides a cell penetrating peptide derived from ZEBRA, which is optionally linked to a cargo molecule, such as at least one antigen or antigenic epitope. The present invention also provides a complex comprising the cell penetrating peptide and the cargo molecule. In particular, compositions, such as a pharmaceutical compositions and vaccines are provided, which may be useful for example in the prevention and/or treatment of a diseases and/or a disorder including cancer, hematological disorders, infectious diseases, autoimmunity disorders and transplant rejections.
Claims34
A cell penetrating peptide comprising an amino acid sequence sharing at least 80% sequence identity with SEQ ID NO:
- 1, wherein the amino acid sequence sharing at least 80% sequence identity with SEQ ID NO:
- 1:
- provides cell penetrating functionality;
- has a serine at position 12;
- and
- has a length of at least 36 amino acids in total.
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Dependencies are inferred from the claim text.