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US 2018/0125966 A1Published application
Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals & methods for formulation thereof
AssigneeUniversal Stabilization Technologies, Inc.
InventorVictor Bronshtein
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Abstract
The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications.
Claims4
A therapeutic composition, comprising:
- an amount of inactivated but therapeutically active (IBTA) biopharmaceuticals immobilized in a dry amorphous carbohydrate-glass, said biopharmaceuticals characterized as being inactivated by irradiation while in the dry state;
- wherein said composition is ambient-temperature stable.
Dependencies are inferred from the claim text.