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US 2018/0119164 A1Published application
Nucleic Acid Molecule and Uses Thereof
AssigneeUniversitäT FüR Bodenkultur Wien
InventorsAndreas Loos, Hertha Steinkellner, Lukas Mach
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Abstract
The present invention relates to a nucleic acid molecule encoding a) a modified tyrosylprotein sulfotransferase of a wildtype tyrosylprotein sulfotransferase, wherein the cytoplasmic transmembrane stem (CTS) region of the wild-type tyrosylprotein sulfotransferase is replaced by a heterologous CTS region, or b) a fusion protein comprising a catalytically active fragment of a tyrosylprotein sulfotransferase fused to a heterologous CTS region.
Claims16
A nucleic acid molecule encoding
- a) a modified tyrosylprotein sulfotransferase of a wildtype tyrosylprotein sulfotransferase, wherein the cytoplasmic transmembrane stem (CTS) region of the wild-type tyrosylprotein sulfotransferase is replaced by a heterologous CTS region, or
- b) a fusion protein comprising a catalytically active fragment of a tyrosylprotein sulfotransferase fused to a heterologous CTS region.
Dependencies are inferred from the claim text.