Analyte Sensing for Eye Injuries and Conditions
AssigneesThe Board of Trustees of the University of Illinois, Carle Health Care Incorporated
InventorsDipanjan Pan, Santosh Kumar Misra, Manas Ranjan Gartia, Leanne T. Labriola
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Abstract
A biosensor for the detection of an analyte such as ascorbic acid is provided. Also provided is a device comprising the biosensor. In addition, methods of detecting analytes such as ascorbic acid in a sample, and methods of a point-of-care diagnosis of eye disease and eye injury are provided.
Claims23
A biosensor for the detection of an analyte, the biosensor comprising:
- a layer of graphene nanoplatelets, carbon nanotubes, or fullerene, a layer of one or more polymers on the layer of graphene nanoplatelets, carbon nanotubes, or fullerene, a layer of a ligand for the analyte on the polymer layer;
- and at least one sensor electrode.
A method of diagnosing an eye condition in a subject comprising detecting the amount of ascorbic acid in a tear film sample from the subject and diagnosing an eye condition in the subject where the amount of ascorbic acid is elevated as compared to a control standard or control sample.
Dependencies are inferred from the claim text.