Increased Production of Terpenes and Terpenoids
AssigneeEvolva SA
InventorsThomas M. Ostergaard Tange, Michael Naesby, Christophe Folly, Fanny Delegrange, Jens Houghton-Larsen, Simon Carlsen
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Abstract
This invention provides recombinant cells and methods for producing terpenes and terpenoids by increasing production or accumulation or both of isoprenoid precursors thereof.
Claims22
1-49. (canceled)
A method for producing a terpene or a terpenoid in a recombinant host cell, comprising culturing the recombinant host cell under conditions wherein the terpene or terpenoid is produced in the recombinant host cell, wherein the recombinant host cell is genetically engineered to produce reduced expression of an endogenous farnesyl diphosphate (FPP) synthase, an endogenous geranyl diphosphate (GPP) synthase or an endogenous enzyme having both FPP synthase and GPP synthase activity.
Dependencies are inferred from the claim text.