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US 2018/0078638 A1Published application
Isg15 and its use as an adjuvant
AssigneeThe Trustees of the University of Pennsylvania
InventorsDavid Weiner, Daniel Villarreal
Life of this patent
Estimating the term…
Abstract
Disclosed herein is a vaccine comprising an antigen and ISG15. Also disclosed herein is a method for increasing an immune response in a subject in need thereof. Further disclosed herein is a method for treating a subject in need thereof. The methods may comprise administering the vaccine to the subject.
Claims32
A vaccine comprising an antigen and ISG15.
A nucleic acid molecule comprising one or more nucleotide sequences selected from the group consisting of:
- a nucleotide sequence having at least about 95% identity to a nucleotide sequence as set forth in SEQ ID NO:1, a nucleotide sequence as set forth in SEQ ID NO:1, a nucleotide sequence having at least about 95% identity to a nucleotide sequence as set forth in SEQ ID NO:3, a nucleotide sequence as set forth in SEQ ID NO:3, a nucleotide sequence having at least about 95% identity to a nucleotide sequence as set forth in SEQ ID NO:5, a nucleotide sequence as set forth in SEQ ID NO:5, a nucleotide sequence having at least about 95% identity to a nucleotide sequence as set forth in SEQ ID NO:7, and a nucleotide sequence as set forth in SEQ ID NO:7, a nucleotide sequence having at least about 95% identity to a nucleotide sequence as set forth in SEQ ID NO:9, a nucleotide sequence as set forth in SEQ ID NO:9, and any combination thereof.
Dependencies are inferred from the claim text.