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US 2018/0055942 A1Published application
Ionically Crosslinked Polyelectrolytes as Underwater Adhesives and Controlled Release Vehicles
AssigneeThe University of Toledo
InventorsYakov Lapitsky, Yan Huang
Life of this patent
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Abstract
Underwater adhesive materials, methods of making the same, and methods of using the same are described.
Claims20
A method for controllably releasing a small molecule comprising:
- adding a small molecule to either (i) a first solution comprising non-polysaccharide polymer having two or more amine groups, or (ii) a second solution comprising a multivalent phosphate crosslinker;
- mixing the first solution with the second solution, at a pH ranging from about 4 to about 10, to form an adhesive gel;
- and
- applying the adhesive gel to a target location, wherein the small molecule is released from the adhesive gel over a period of time.
1 more element
A method of delivering an adhesive to a target location comprising:
- mixing a polyamine with a multivalent phosphate crosslinker in acidic or basic solution to obtain a mixture;
- injecting the mixture to a target location;
- and
- adjusting the pH of the mixture to ambient pH to form an adhesive gel-like complex in the target location.
1 more element
A method of delivering an adhesive to a target location comprising:
- mixing a polyamine with a multivalent phosphate crosslinker in a solution to obtain a mixture;
- injecting the mixture to a target location;
- and
- adjusting the ionic strength of the solution to form an adhesive gel-like complex in the target location.
1 more element
A composition comprising:
- a non-polysaccharide polymer having two or more amine groups;
- and
- a multivalent phosphate crosslinker;
- the composition comprising an ionically crosslinked network that forms a gel-like coacervate at a pH in the range of from about 4 to about 10.
1 more element
Dependencies are inferred from the claim text.