US 2018/0049962 A1 · LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE

Abstract

The present disclosure relates to methods and compositions comprising naturally occurring light absorbing molecules for preventing damages from light exposure. Specific embodiments of this disclosure include fluorescent proteins from Brachiostoma lanceolatum.

Claims8

Dependent claims

-4. (canceled)

A method for protecting the skin from light damage in a subject in need thereof, comprising topically administering a formulation comprising a dermatologically acceptable carrier or a vehicle and a functional Brachiostoma light absorbing protein polypeptide comprising the sequence from the N-terminus:

(SEQ ID NO:
15)
Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-
Xaa11-Xaa12-Xaa13-Xaa14-Xaa15-Xaa16-Xaa17-Xaa18-
Xaa19-Xaa20-Xaa21-Xaa22-Xaa23-Xaa24-Xaa25-Xaa26-
Xaa27-Xaa28-Xaa29-Xaa30-Xaa31-Xaa32-Xaa33-Xaa34-
Xaa35-Xaa36-Xaa37-Xaa38-Xaa39-Xaa40-Xaa41-Xaa42-
Xaa43-Xaa44-Glu45-Xaa46-Xaa47-Xaa48-Xaa49-Xaa50-
Xaa51-Xaa52-Xaa53-Xaa54-Xaa55-Xaa56-Xaa57-Xaa58-
Xaa59-Xaa60-Trp61-Xaa62-Xaa63-Xaa64-Pro65-Xaa66-
Xaa67-Gly68-Tyr69-Gly70-Phe71-His72-Xaa73-Xaa74-
Xaa75-Xaa76-Xaa77-Xaa78-Xaa79-Xaa80-Xaa81-Xaa82-
Xaa83-Xaa84-Xaa85-Xaa86-Xaa87-Xaa88-Xaa89-Xaa90-
Xaa91-Xaa92-Xaa93-Xaa94-Xaa95-Xaa96-Xaa97-Xaa98-
Xaa99-Xaa100-Xaa101-Xaa102-Xaa103-Xaa104-Xaa105-
Xaa106-Xaa107-Xaa108-Xaa109-Xaa110-Xaa111-Tyr112-
Xaa113-Xaa114-Xaa115-Xaa116-Xaa117-Xaa118-Xaa119-
Xaa120-Xaa121-Xaa122-Xaa123-Xaa124-Xaa125-Xaa126-
Xaa127-Xaa128-Xaa129-Xaa130-Xaa131-Xaa132-Xaa133-
Xaa134-Xaa135-Xaa136-Xaa137-Xaa138-Xaa139-Xaa140-
Xaa141-Xaa142-Xaa143-Xaa144-Xaa145-Xaa146-Xaa147-
Xaa148-Xaa149-Xaa150-Xaa151-Xaa152-Xaa153-Xaa154-
Xaa155-Xaa156-Xaa157-Xaa158-Xaa159-Xaa160-Xaa161-
Xaa162-Xaa163-Xaa164-Xaa165-Xaa166-Trp167-Xaa168-
Tyr169-Xaa170-Xaa171-Xaa172-Xaa173-Xaa174-Xaa175-
Xaa176-Xaa177-Xaa178-Xaa179-Xaa180-Xaa181-Xaa182-
Xaa183-Xaa184-Xaa185-Xaa186-Xaa187-Xaa188-Xaa189-
Xaa190-Xaa191-Xaa192-Xaa193-Xaa194-Xaa195-Xaa196-
Xaa197-Xaa198-Xaa199-Xaa200-Xaa201-Xaa202-Xaa203-
Xaa204-Arg205-Xaa206-Xaa207-Xaa208-Xaa209-Xaa210-
Xaa211-Xaa212-Xaa213-Xaa214-Xaa215-Xaa216-Xaa217-
Xaa218-Xaa219-Glu220-Xaa221-Xaa222-Xaa223-Xaa224-
Xaa225.

30 more elements

Dependencies are inferred from the claim text.

Facts

Application

15/682,388Filed 21 Aug 2017

Priority

9 Aug 2010

Published

22 Feb 2018

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 8/64
Containing organic compounds: proteins; Peptides; Derivatives or degradation products thereof
A61K 8/987
Of animal origin: of species other than mammals or birds
A61K 38/1767
From animals; from humans: from invertebrates
A61Q 17/04
Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g.…

Family

Application61/371,741Us provisional application · filed 9 Aug 2010

Application13/206,420Continuation in part · filed 9 Aug 2011

Application14/961,678Continuation in part · filed 7 Dec 2015

Application15/682,388Continuation in part

US 10,842,728 B2Related patent

US 2012/0093737 A1Published application

US 2016/0193132 A1Published application

US 9,205,284 B2Related patent

US 9,737,472 B2Related patent

US 2018/0049962 A1This patent

From the US filing history. Foreign family members aren’t listed.

Light-absorbing compositions and methods of use

Life of this patent

Abstract

Claims8

Light-absorbing compositions and methods of use

Life of this patent

Abstract

Claims8