Methods for enhancing the delivery of molecules across the blood brain barrier
AssigneeLAM Therapeutics, Inc.
InventorsTian Xu, Henri Lichenstein, Jonathan M. Rothberg
Life of this patent
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Abstract
The present invention relates to methods and compositions for enhancing the delivery of an agent across the blood brain barrier utilizing a composition comprising an inhibitor of PIKfyve.
Claims33
A method for increasing the transcytosis of an agent across a cell, the method comprising contacting the cell with a composition comprising the agent and contacting the cell with an inhibitor of PIKfyve.
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A method for administering a therapeutic agent to the brain of a subject in need thereof, the method comprising administering to the subject (i) a composition comprising the agent and (ii) an inhibitor of PIKfyve.
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Dependencies are inferred from the claim text.