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AssigneePlant Sensory Systems, LLC
InventorsFrank J. TURANO, Kathleen A. TURANO, Peter S. CARLSON, Alan M. KINNERSLEY
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The present invention describes an approach to increase taurine or hypotaurine production in prokaryotes. More particularly, the invention relates to genetic transformation of organisms with genes that encode proteins that catalyze the conversion of cysteine to taurine, methionine to taurine, cysteamine to taurine, or alanine to taurine. The invention describes methods for the use of polynucleotides that encode cysteine dioxygenase (CDO) and sulfinoalanine decarboxylase (SAD) polypeptides in prokaryotes to increase taurine, hypotaurine or taurine precursor production. The preferred embodiment of the invention is in plants but other organisms may be used. Increased taurine production in prokaryotes could be used as nutraceutical, pharmaceutical, or therapeutic compounds or as a supplement in animal feed.
A cell comprising an expression cassette stably incorporated in its genome, the expression cassette comprising a promoter operably linked to an exogenous polynucleotide that is operably linked to a terminator, wherein the exogenous polynucleotide encodes a sulfinoalanine decarboxylase (SAD).
A seed having stably incorporated in its genome an exogenous polynucleotide encoding a sulfinoalanine decarboxylase (SAD) protein.
A plant having stably incorporated in its genome an exogenous polynucleotide encoding a sulfinoalanine decarboxylase (SAD) protein.
Dependencies are inferred from the claim text.