# US 2018/0026730 A1 · Patch system for in-situ therapeutic treatment > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2018/0026730 A1 - Document ID: US20180026730A1 - Status: Published application - Kind: A1 - Application number: 15/676,611 - Filed: 2017-08-14 - Published: 2018-01-25 - Earliest claimed: 2016-07-21 - Assignees: Intel Corporation - Applicants: Intel Corporation - Inventors: Aleksandar Aleksov; Sasha N. Oster; Feras Eid; Adel A. Elsherbini; Johanna M. Swan; Amit Sudhir Baxi; Vincent S. Mageshkumar; Kumar Ranganathan; Wen-Ling M. Huang - Web page: https://patentgrep.com/patent/US20180026730A1 ## CPC - A61N 7/00: Ultrasound therapy (lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 {; using ultrasound for introducing media into the body A61M37/0092}) - A61B 5/0024: {for multiple sensor units attached to the patient, e.g. using a body or personal area network} - A61B 5/01: Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) - A61B 5/0205: Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition - A61B 5/021: Measuring pressure in heart or blood vessels - A61B 5/1102: {Ballistocardiography} - A61B 5/1107: {Measuring contraction of parts of the body, e.g. organ or muscle} - A61B 5/1121: {Determining geometric values, e.g. centre of rotation or angular range of movement} - A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement} - A61B 5/14546: {for measuring analytes not otherwise provided for, e.g. ions, cytochromes} - A61B 5/4839: {combined with drug delivery} - A61B 5/4869: {Determining body composition} - A61B 5/6833: {Adhesive patches} - A61M 5/14248: {of the skin patch type} - A61N 1/0492: {Patch electrodes (A61N1/0412, A61N1/0428 take precedence)} - H04B 5/22: Capacitive coupling - A61F 7/007: {characterised by electric heating} - A61N 1/0484: {Garment electrodes worn by the patient} - A61N 1/3603: {Control systems} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - H04B: TRANSMISSION - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract Discussed generally herein are methods and devices including or providing a patch system that can help in diagnosing a medical condition and/or provide therapy to a user. A body-area network can include a plurality of communicatively coupled patches that communicate with an intermediate device. The intermediate device can provide data representative of a biological parameter monitored by the patches to proper personnel, such as for diagnosis and/or response. ## Claims ### Claim 1 A system comprising: a first patch including: a first flexible and/or stretchable substrate, a first adhesive on the first substrate, the first adhesive configured to temporarily attach the first patch to skin of a user, and first electronics on or at least partially in the first substrate, the first electronics including at least one first component to provide therapy to the user and a first wireless radio, and a second patch including: a second flexible and or stretchable substrate, a second adhesive on the second substrate, the second adhesive configured to temporarily attach the second patch to the skin of the user, and second electronics on or at least partially in the second flexible, stretchable substrate, the second electronics including at least one second component to monitor a first biological parameter of the user and a second wireless radio; and the second wireless radio communicatively coupled to the first wireless radio of the first electronics, the second wireless radio to provide one or more signals indicative of the first biological parameter to the first patch. ### Claim 2 (depends on 1) The system of claim 1, wherein the first electronics are to adjust an amount of the therapy provided by the first patch in response to the provided one or more signals. ### Claim 3 (depends on 1) The system of claim 1, wherein the at least one first component includes at least one of a vesicle and a needle and the therapy includes medicine, the at least one first component includes an ultrasonic transducer and the therapy include ultrasonic waves, and the at least one first component includes one or more conductive pads coupled to power delivery circuitry and the therapy includes electrical stimulation. ### Claim 4 (depends on 3) The system of claim 3, wherein the first patch operates in a master role including the first wireless radio communicatively coupled to the second wireless radio and the second wireless radio communicates to another device through the first patch. ### Claim 5 (depends on 1) The system of claim 1, further comprising: a third patch including: a third flexible and/or stretchable substrate, a third adhesive on the third substrate, the third adhesive configured to temporarily attach the third patch to the skin of the user, and third electronics on or at least partially in the third substrate, the third electronics including at least one third component to monitor a second biological parameter of the user and a third wireless radio, the second biological parameter different from the first biological parameter, the third wireless radio communicatively coupled to at least one of the first wireless radio and the second wireless radio. ### Claim 6 (depends on 5) The system of claim 5, wherein the third wireless radio is communicatively coupled to the second wireless radio and the second wireless radio is communicatively coupled to the first wireless radio and the second and third wireless radios are not communicatively coupled to another device to which the first wireless radio is communicatively coupled. ### Claim 7 (depends on 1) The system of claim 1, wherein the first biological parameter includes one of flexion, contraction, stretch, temperature, electrical activity a specific force, angular rate, magnetic field, salinity, muscular activity of the heart, electrical activity of the heart, pulse, oxygen content, lactate content, pressure, organ or conduit volume, blood pressure, blood glucose level, and electro-dermal activity. ### Claim 8 (depends on 1) The system of claim 1, wherein the second patch is configured to be situated partially in an armpit with a first portion of the electronics on a first electronics substrate configured to be situated in the armpit and a second portion of the electronics on a second electronics substrate electrically coupled to the first portion of the electronics and configured to be situated outside of the armpit. ### Claim 9 (depends on 8) The system of claim 8, wherein the first electronics substrate is flexible and the second electronics substrate is rigid. ### Claim 10 (depends on 1) The system of claim 1, wherein the second wireless radio and the first wireless radio are both further configured to communicate directly with another device. ### Claim 11 A method comprising: attaching, using a first adhesive on a first flexible and/or stretchable substrate of a first patch, the first patch to skin of a user at a first location; attaching, using a second adhesive on a second flexible and/or stretchable substrate of a second patch, the second patch to the skin of the user at a second, different location; monitoring, using second electronics on or at least partially in the second substrate, a first biological parameter of the user during a first time frame; providing, using a second wireless radio of the second electronics, signals corresponding to the first biological parameter to a first wireless radio of the first patch; and providing, using first electronics on or at least partially in the first substrate and during the first time frame, a therapy to the user. ### Claim 12 (depends on 11) The method of claim 11, wherein a first component of the first electronics includes an ultrasonic transducer and the therapy includes ultrasonic therapy. ### Claim 13 (depends on 11) The method of claim 11, wherein a first component of the first electronics includes at least one conductive pad and the therapy includes electro-therapy provided through the at least one conductive pad. ### Claim 14 (depends on 11) The method of claim 11, wherein a first component of the first electronics includes at least one of a vesicle and a needle and the therapy includes a medication provided through the at least one vesicle and the at least one needle. ### Claim 15 (depends on 11) The method of claim 11, further comprising: attaching, using a third adhesive on a third flexible and/or stretchable substrate, a third patch to skin of a user at a third location; monitoring, using third electronics on or at least partially in the third substrate, a second biological parameter of the user during the first time frame; and providing, using one of the first wireless radio and the second wireless radio, signals corresponding to the second biological parameter to the first wireless radio. ### Claim 16 (depends on 11) The method of claim 11, further comprising: receiving, from the second wireless radio, signals indicating a change to the therapy provided by the first electronics, the change to the therapy determined based on the signals corresponding to the first biological parameter; and adjusting an amount or a schedule of therapy delivery based on the signals from the second wireless radio. ### Claim 17 A body area network comprising: at least two patches, each of the at least two patches including: a flexible and/or stretchable substrate, an adhesive on the flexible and/or stretchable substrate, the adhesive configured to temporarily attach the patch to skin of a user, and electronics on or at least partially in the flexible and/or stretchable substrate, the electronics including a wireless radio and at least one of a first component to provide therapy to the user and a second component to monitor a first biological parameter of the user, and wherein electronics of a first patch of the at least two patches includes processing circuitry to receive data corresponding to the biological parameter and adjust an amount of the therapy provided by the first patch based on the received data. ### Claim 18 (depends on 17) The body area network of claim 17, wherein a second patch is configured to communicate with another device only through the wireless radio of the first patch. ### Claim 19 (depends on 17) The body area network of claim 17, wherein only one patch of the at least two patches is communicatively coupled to a device other than the at least two patches and is to communicate data from all patches of the at least two patches to the device. ### Claim 20 (depends on 17) The body area network of claim 17, wherein a first patch of the at least two patches is configured to perform a role of a master patch during a first time frame and all other patches of the at least two patches provide data to the first patch during the first time frame and a second patch of the at least two patches is configured to perform the role of the master patch during a second time frame different from the first time frame and all other patches of the at least two patches provide data to the second patch during the second time frame.