Disconnector Device
AssigneeGe Healthcare Limited
InventorPhilippe Dumont
Life of this patent
Estimating the term…
Abstract
The present invention relates to an automated radiosynthesis device adapted for enhanced automatic disconnection of a disposable kit once a radiosynthesis has been carried out. The automated radiosynthesis device of the invention therefore reduces the time to remove the disposable kit from the radiosynthesis device and reduces radiation exposure to the operator.
Claims19
The automated radiosynthesis device as defined in claim 1, wherein said plurality of connectors is selected from the group comprising fasteners, and fluidic connectors.
The automated radiosynthesis device as defined in claim 1, wherein said disposable kit is suitable for the synthesis of a radiotracer compound.
The automated radiosynthesis device as defined in claim 1, wherein said disposable kit is a single-use cassette.
The automated radiosynthesis device as defined in claim 1, wherein said plurality of actuators is selected from the group comprising rotatable arms for stopcocks of valves, linear actuators, arms that press onto reagent vials and pinch valves.
The automated radiosynthesis device as defined in claim 1, wherein said moving parts of said disposable kit are selected from the group comprising reagent vials, syringes and valves.
The automated radiosynthesis device as defined in claim 1, wherein said control unit includes software comprising instructions for a particular radiosynthesis method to be carried out on said disposable kit attached to said automated radiosynthesis device.
The automated radiosynthesis device as defined in claim 1, wherein said automated attachment means comprises a drawer into which said disposable kit can be loaded and wherein said drawer is moveable between a first position for loading and/or disconnecting said disposable kit and a second position where said loaded disposable kit is attached to said face of said automated radiosynthesis device.
The automated radiosynthesis device as defined in claim 1, wherein the body of the disconnection device is configured to form rigid arms defining said aperture therebetween.
The automated radiosynthesis device as defined in claim 1, wherein said disconnector device is made from a metal or a rigid plastic.
The automated radiosynthesis device as defined in claim 1, wherein said disconnector device is fixed to said automated attachment means.
The method as defined in claim 15, wherein said at least one line is connected to a product collection vial.
A radiosynthesis method comprising:
- (a) providing an automated radiosynthesis device as defined in claim 1;
- (b) attaching a disposable kit as defined in claim 1 to said automated radiosynthesis device wherein said disposable kit comprises at least one line having a connector at the end distal to the disposable kit;
- (c) connecting said at least one line to a respective vial;
- (d) carrying out a radiosynthesis on said attached disposable kit;
- (e) disconnecting said disposable kit following said step (c) wherein said disconnecting includes disconnecting said at least one line from its respective vial by means of a disconnector device as defined in claim 1.
The method as defined in claim 17 wherein said at least one line is connected to a 18O-water recovery vial.
The method as defined in claim 17 wherein said at least one line is connected to a product collection vial.
Dependencies are inferred from the claim text.