# US 2018/0021484 A1 · Medical instrument lubricant system and application method thereof

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- Number: US 2018/0021484 A1
- Document ID: US20180021484A1
- Status: Published application
- Kind: A1
- Application number: 15/547,493
- Filed: 2016-01-11
- Published: 2018-01-25
- Earliest claimed: 2015-01-30
- Assignees: Jb Medical, Inc.
- Applicants: Jb Medical, Inc.
- Inventors: Jibin YANG; Yaguo JIANG
- Web page: https://patentgrep.com/patent/US20180021484A1

## CPC

- A61L 31/10: Macromolecular materials
- C10M 107/50: containing silicon
- C08G 77/16: to hydroxy groups
- C08L 83/04: Polysiloxanes
- C10M 173/00: Lubricating compositions containing more than 10% water
- C10M 2201/102: Silicates
- C10M 2207/021: having hydroxy groups bound to acyclic or cycloaliphatic carbon atoms
- C10M 2229/02: Unspecified siloxanes; Silicones
- C10N 2010/08: Groups 4 or 14
- C10N 2020/02: Viscosity; Viscosity index
- C10N 2020/04: Molecular weight; Molecular weight distribution
- C10N 2040/50: {Medical uses}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- C10M: LUBRICATING COMPOSITIONS (well drilling compositions C09K8/02); USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION (mould release, i.e. separating, agents for metals B22C3/00, for plastics or substances in a plastic state, in general B29C33/56, for glass C03B40/02; textile lubricating compositions D06M11/00, D06M13/00, D06M15/00; immersion oils for microscopy G02B21/33)
- C08G: MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06)
- C10N: INDEXING SCHEME ASSOCIATED WITH SUBCLASS C10M RELATING TO LUBRICATING COMPOSITIONS

## Abstract

The present invention disclosed a lubricant system and methods of use. Said lubricant system comprises siloxane polymers with viscosity greater than 100 centistokes and cross-linking agents that can promote siloxane polymers curing rapidly in ambient conditions. The lubricant system comprises further hydroxy siloxane polymers, siloxane coupling agent, catalyst and volatile carrier solvents. The surfaces of medical devices are coated at least once, a solid lubrication film can be quickly formed, and the film has a very excellent lubricating performance and wide applications. The methods of use are simple, easy to implement and control, and is particularly suitable for rapid automatic production lines, and thus is of great economic value.

## Claims

### Claim 1

A medical device lubricant system comprises:
siloxane polymers with viscosity greater than 100 centistokes; and cross-linking agents that can promote siloxane polymers curing rapidly in ambient conditions.

### Claim 2 (depends on 1)

A medical device lubricant system according to claim 1, wherein said siloxane polymers comprise selected compounds defined by the following structure:
Wherein m+n is an integer between 6 to 2000; the chain length of R(1/2/3/4/5/6) is 1˜20; R group are an alkyl group, an aryl group and mixture thereof;
R1, R2, R3, R4, R5, R6 are the same or different.

### Claim 3 (depends on 1)

A medical device lubricant system according to claim 1, wherein said siloxane polymers' viscosity is between 100 centistokes to 30,000 centistokes, molecular weight is between 6000 to 90000.

### Claim 4 (depends on 1)

A medical device lubricant system according to claim 1, wherein said siloxane polymers comprise selected hydroxy siloxane polymers defined by the following structure:
Wherein m+n is an integer between 150 to 1000; R group are an alkyl group, an aryl group, trifluoro propyl and mixture thereof; R1, R2, R3, R4, R5, R6 are the same or different.

### Claim 5 (depends on 4)

A medical device lubricant system according to claim 4, wherein said hydroxy siloxane polymers' viscosity is between 1000 centistokes to 8000 centistokes, molecular weight is between 30000 to 60000.

### Claim 6 (depends on 1)

A medical device lubricant system according to claim 1, wherein said lubricant further comprises siloxane coupling agent defined by the following structure:
—Si Rx1(OR2)3-x
Wherein X is an integer 0≦X<2; R1 are vinyl group, alkyl group terminated with amino, epoxy, halogenated groups; R2 are methyl, ethyl groups.

### Claim 7 (depends on 1)

A medical device lubricant system according to claim 1, wherein said cross-linking agents comprise selected compounds defined by the following structure: Ra1SiRb2(OR3)4-a-b
Wherein a is an integer 0≦a≦2; b is an integer 0≦b<4; R1 are vinyl, alkyl, vinyl groups; R2 are amino group; R3 are alkyl, hydrogen, alkenyl, amino, acyl, aryl, carbonyl groups.

### Claim 8 (depends on 1)

A medical device lubricant system according to claim 1 further comprises catalysts, wherein said catalysts are organic tin catalysts.

### Claim 9 (depends on 1)

A medical device lubricant system according to claim 1 further comprises volatile carrier solvents, wherein said volatile carrier solvents are hydrofluoroether or chlorofluorocarbon solvents.

### Claim 10 (depends on 1)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 1 and reactive product thereof.

### Claim 11 (depends on 10)

The methods of use of a medical device lubricant system according to claim 10 comprise methods of dipping, spraying, brushing, painting and jet to coat said lubricant to the surface of medical devices.

### Claim 12 (depends on 10)

The methods of use of a medical device lubricant system according to claim 10 further comprise coating of said lubricant to the metallic and polymer surfaces of medical devices.

### Claim 13 (depends on 2)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 2 and reactive product thereof.

### Claim 14 (depends on 3)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 3 and reactive product thereof.

### Claim 15 (depends on 4)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 4 and reactive product thereof.

### Claim 16 (depends on 5)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 5 and reactive product thereof.

### Claim 17 (depends on 6)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 6 and reactive product thereof.

### Claim 18 (depends on 7)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 7 and reactive product thereof.

### Claim 19 (depends on 8)

The methods of use of a medical device lubricant system comprise coating at least one layer of said lubricant on the surface of medical devices, wherein said lubricant coatings comprise any compositions in claim 8 and reactive product thereof.