Systems and methods for nucleic acid-based identification

A system comprising:

• a first instrument that analyzes a nucleic acid sample and produces a first set of data from a first set of polymorphic genetic markers for a nucleic acid sample;
• a second instrument that analyzes the nucleic acid sample and produces a second set of data from a second set of polymorphic genetic markers for the nucleic acid sample, wherein the polymorphic genetic markers comprise short tandem repeats (STRs), indels and single nucleotide polymorphisms (SNPs);
• a database that provides linkage information between the first set of polymorphic genetic markers and the second set of polymorphic genetic markers;
• a processor in communication with the first instrument, the second instrument, and the database that receives the first set of data from the first instrument, the second set of data from the second instrument, and the linkage information from the database and that selects a usable value for a polymorphic genetic marker from the second set of data;
• searches the linkage information of the database for the polymorphic genetic marker;
• determines that the polymorphic genetic marker is not linked to any of the polymorphic genetic markers in the first set of data that have usable values;
• and
• calculates a predictive index of identity based on the usable values in the first set of data and the usable value for the polymorphic genetic marker from the second set of data, wherein the usable value for the polymorphic genetic marker from the second set of data replaces an unusable value in the first set of data in the calculation of the predictive index of identity and wherein the first set of polymorphic genetic markers and the second set of polymorphic genetic markers are different types of polymorphic genetic markers.