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US 2018/0008981 A1Published application
Target Analysis Chip and Target Analysis Method
AssigneesARKRAY, Inc., National University Corporation Kyoto Institute of Technology
InventorsAkira Murakami, Akio Kobori, Asako Yamayoshi, Yuichiro Noda, Masayuki Kondo
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Abstract
The present invention provides a novel target analysis chip and analysis method for directly detecting a target such as a microRNA without performing PCR.
Claims21
A target analysis chip, comprising a substrate, the substrate comprising a reaction section at which a sample containing a target is made to react with a reagent, a detection section at which label detection is performed, and a flow channel that communicates the reaction section with the detection section, wherein:
- the reagent comprises a carrier;
- the carrier comprises a labeled probe immobilized thereon, the labeled probe being configured to bind to the target, and the carrier having specific gravity of greater than 1 and being configured to form a conjugate with the target;
- the flow channel comprises a movement controller configured to control movement of the carrier from the reaction section to the detection section;
- the movement controller comprises a hydrophobic inner wall in the flow channel;
- and
- due to the movement controller, the conjugate is made to move to the detection section through the flow channel when a centrifugal force (C2), that is larger than a resistance force (R) caused by the hydrophobicity of the flow channel, is applied.
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(canceled)
Dependencies are inferred from the claim text.