Ready-to-use device for mouse bone marrow cells isolation

Abstract

The present invention is, in combination, a bone marrow isolation tube and a centrifuge tube. The combination includes a centrifuge tube which defines a tube cavity and includes an upper cylindrical section connected to a lower tapered section which terminates at a bottom reservoir. The isolation tube is adapted to be received within the centrifuge tube cavity. The isolation tube includes a body with a tubular shaped outer surface wherein the interior of the isolation tube defines a lumen which includes an upper cylindrical lumen section and a lower conical lumen section terminating at an orifice. The isolation tube includes at least one wing extending radially outward from the outer surface of the isolation tube. The wing is configured to make contact with the interior surface of the centrifuge tube and wedge the isolation tube into the tapered section of the centrifuge tube during centrifuging. The present invention is also, in combination, a bone marrow isolation tube and a centrifuge tube. The centrifuge tube defines a tube cavity and includes at least two support members defining an insertion space and attached to the interior surface in an upper cylindrical section, the upper cylindrical section connected to a lower tapered section which terminates at a bottom reservoir. The isolation tube is adapted to be received within the insertion space with a flange that is configured to make contact with the support members of the centrifuge tube thereby wedging the isolation tube into the insertion space of the centrifuge tube during centrifuging.

Dependencies are inferred from the claim text.