System and Method for Controlled Manufacturing of Mono-Disperse Microbubbles

A system for controlled manufacturing of microbubbles, comprising:

• a microbubble generation unit having a first inlet for receiving a dispersed phase fluid, a second inlet for receiving a continuous phase fluid, and a bubble formation channel in which microbubbles are generated using the received dispersed phase fluid and the received continuous phase fluid, wherein the bubble formation channel has a width in the range of 15-35 micrometer, and a height in the range of 10-30 micrometer;
• a liquid pressurization unit having an inlet for receiving a second pressure regulated gaseous medium from a source of said second pressure regulated gaseous medium and being configured for outputting a flow of a pressurized liquid to the second inlet of the microbubble generation unit in dependence of a flow and/or pressure of the received second pressure regulated gaseous medium, wherein the first inlet of the microbubble generation unit is connected to a source of a first pressure regulated gaseous medium;
• a first release valve unit arranged in between the source of the first pressure regulated gaseous medium and the first inlet of the microbubble generation unit and being configured for releasing the first pressure regulated gaseous medium;
• a second release valve unit arranged in between the source of the second pressure regulated gaseous medium and the inlet of the liquid pressurization unit and being configured for releasing the second pressure regulated gaseous medium;
• and
• a control unit for controlling the first and second release valves in dependence of a comparison between a pressure of the first pressure regulated gaseous medium and a first pressure setting and between a pressure of the second pressure regulated gaseous medium and a second pressure setting, respectively.