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US 2018/0008745 A1Published application
Tissue matrices incorporating multiple tissue types
AssigneeLifeCell Corporation
InventorsSangwook Park, Hui Xu, Aaron Barere, Israel Jessop, Mrinal Shah, Nathaniel Bachrach
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Abstract
The present disclosure provides tissue products produced from extracellular tissue matrices. The tissue products can include acellular extracellular matrices including combinations of different tissue types. The combination can harness various properties of the different tissues to provide improved composite structures with desired mechanical and/or biologic properties.
Claims27
A tissue product, comprising:
- a first component comprising an intact acellular tissue matrix;
- and
- a second component comprising a porous acellular tissue matrix sponge covering at least a portion of the intact acellular tissue matrix, wherein the porous acellular tissue matrix sponge comprises a tissue matrix that has been mechanically homogenized, resuspended, and stabilized, and wherein the intact acellular tissue matrix and porous acellular tissue matrix sponge are attached such that the intact acellular tissue matrix provides mechanical support to the porous acellular tissue matrix sponge.
A tissue product, comprising:
- a first component comprising a sheet of acellular tissue matrix;
- and
- a second component comprising a porous acellular tissue matrix sponge covering at least a portion of the intact acellular tissue matrix, wherein the second component consists essentially of adipose tissue matrix.
A tissue product, comprising:
- a first component comprising a sheet of acellular tissue matrix;
- a second component comprising a sheet of a second acellular tissue matrix derived from a tissue type different than that of the first component;
- and
- a third component comprising a porous acellular tissue matrix sponge, wherein the third component is contained between the first component and the second component.
1 more element
Dependencies are inferred from the claim text.