Lactic-Acid-Bacteria-Containing Composition, Oral Pharmaceutical Composition for Treating HPV Infection and/or HPV-Associated Tumors, and Mucosal Immunity-Inducing Agent
AssigneesThe University of Tokyo, Japan Health Sciences Foundation
InventorsKei Kawana, Shizunobu Igimi
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Abstract
A lactic acid bacterium-containing composition including a lactic acid bacterium having a human papillomavirus (HPV) E7 protein-derived polypeptide on a surface thereof, wherein the HPV E7 protein-derived polypeptide is included in an amount of 0.03 μg to 1.0 μg per 1×108 lactic acid bacteria; a therapeutic oral pharmaceutical composition for at least one of an HPV infectious disease and an HPV-associated tumor which includes the lactic acid bacterium-containing composition; and a mucosal immunity-inducing agent which includes the lactic acid bacterium-containing composition.
Claims15
A lactic acid bacterium-containing composition comprising
- a lactic acid bacterium having a human papillomavirus (HPV) E7 protein-derived polypeptide on a surface thereof,
- wherein the HPV E7 protein-derived polypeptide is included in an amount of 0.03 μg to 1.0 μg per 1×10′ lactic acid bacteria.
A therapeutic oral pharmaceutical composition for at least one of an HPV infectious disease and an HPV-associated tumor, the composition comprising
- a lactic acid bacterium-containing composition comprising a lactic acid bacterium having a human papillomavirus (HPV) E7 protein-derived polypeptide on a surface thereof,
- wherein the HPV E7 protein-derived polypeptide is included in an amount of 0.03 μg to 1.0 μper 1×108 lactic acid bacteria.
A mucosal immunity-inducing agent comprising
- a lactic acid bacterium-containing composition comprising a lactic acid bacterium having a human papillomavirus (HPV) E7 protein-derived polypeptide on a surface thereof,
- wherein the HPV E7 protein-derived polypeptide is included in an amount of 0.03 μg to 1.0 μg per 1×108 lactic acid bacteria.
Dependencies are inferred from the claim text.