Extracts of edible fungi enriched in vitamin d and compostions thereof and their use in the treatment of immune-related disorders
AssigneesGavish-Galilee Bio Applications Ltd., Hadasit Medical Research Services and Development Ltd.
InventorsDan LEVANON, Yaron ILAN, Ofer DANAI
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Abstract
A vitamin D2-enriched biomass of an edible fungus, extracts and compositions thereof are provided, for use in delaying onset of, treating, ameliorating or protecting from an immune-related or inflammatory related disease, disorder or condition, wherein the level of vitamin D2 in said biomass is at least 80 IU/gr.
Claims23
A method for delaying onset of, treating, ameliorating or protecting from an immune-related or inflammatory related disease, disorder or condition in a mammalian subject, said method comprising administering to said subject a therapeutically effective amount of vitamin D2-enriched biomass of an edible fungus or an extract thereof,
- wherein the level of vitamin D2 in said biomass is at least 80 IU/gr.
A method for delaying onset of, treating, ameliorating or protecting from an immune-related or inflammatory related disease, disorder or condition in a mammalian subject, said method comprising administering to said subject a therapeutically effective amount of vitamin D2-enriched biomass of an edible fungus,
- wherein vitamin D2 is present in said biomass at a level that is at least about 2 times higher than the level of vitamin D2 in an biomass of an edible fungus that has not been exposed to UVB radiation.
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A composition comprising a biomass or extract of an untreated edible fungus and vitamin D2, wherein the level of vitamin D2 is at least 80 IU/gr.
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A kit for use in delaying onset of, treating, ameliorating or protecting from an immune-related or inflammatory related disease, disorder or condition, said kit comprising:
- (a) a biomass of an edible fungus;
- (b) an extract obtained from an edible fungus;
- or
- (c) a composition comprising an extract obtained from an edible fungus;
- (d) vitamin D2;
- and
- (e) a leaflet with instructions for administration of a combination of (a), (b) or (c) and (d).
Dependencies are inferred from the claim text.