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US 2018/0008599 A1Published application
Pharmaceutical preparation comprising brexpiprazole and substituted beta-cyclodextrin
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsTetsuya HASEGAWA, Hidekazu TOYOBUKU
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Abstract
Provided is an aqueous pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (compound (I)) or a salt thereof, which shows improved water solubility of compound (I) or a salt thereof achieved by addition of substituted β-cyclodextrin. The present invention provides a pharmaceutical preparation comprising compound (I) or a salt thereof, and substituted β-cyclodextrin.
Claims3
A pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof, and substituted β-cyclodextrin.
Dependencies are inferred from the claim text.