Metallic and protein/polymer nanoparticle constructs, multi-drug vehicle and fabrication methods
OwnerRaghuraman Kannan, Srikar Raman +3inventors
InventorsRaghuraman Kannan, Srikar Raman, Ajit Zambre, Abilash Gangula, Anandhi Upendran
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Abstract
A multidimensional nanoconstruct includes a three-dimensional thiolated protein, gelatin or polymer nanoparticle and exposed metallic nanoparticles bonded to outer surfaces of the particle. In a method of formation, number of metallic nanoparticles that attach to the carrier nanoparticle is controlled via microfluidics or via controlling the reactivity of the metallic nanoparticle and carrier nanoparticle.
Claims33
A method of forming a multi-dimensional metallic and carrier nanoconstruct, the method comprising interacting a solution of metallic nanoparticles with a solution of gelatin, polymer or protein carrier nanoparticles, wherein the carrier nanoparticles comprise a free thiol, and the method further comprises controlling the number of metallic nanoparticles that attach to each carrier nanoparticle via microfluidic control or reactivity control.
A multidimensional nanoconstruct comprising a protein, thiolated gelatin or polymer nanoparticle and exposed metallic nanoparticles bonded to outer surfaces of the particle.
Dependencies are inferred from the claim text.