Controlled release preparations
AssigneePatheon Softgels, Inc.
InventorsEmadEldin M. Hassan, Nachiappan Chidambaram, Aqeel A. Fatmi
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Abstract
Controlled release preparations and soft capsules are provided. Also provided are emulsions and suspensions, including compositions and methods of manufacturing controlled release soft capsules, where the fill contains a suspension and/or an emulsion.
Claims12
A controlled release soft capsule having a shell and a matrix fill comprising an active ingredient or drug, wherein the matrix fill consists of two phases in the form of an emulsion, wherein the emulsion comprises a hydrophilic internal phase consisting essentially of polyethylene glycol of molecular weight ranging from about 200 to about 8000, methyl cellulose and an active ingredient or drug and a lipid or lipophilic external phase;
- and wherein the ratio of the internal phase to external phase is from about 0.5:10 to about 1:1 by weight.
Dependencies are inferred from the claim text.