Cyclodextrin Compositions Encapsulating a Selective ATP Inhibitor and Uses Thereof

A composition comprising a cyclodextrin and a pharmaceutical agent represented in the general formula:

• wherein, independently of each occurrence:
• X represents a halide, a sulfonate, a carboxylate, an alkoxide, or an amine oxide;
• R1 represents OR, H, N(R″)2, C1-C6 alkyl, C6-C12 aryl, C1-C6 heteroalkyl, or C6-C12 heteroaryl;
• R″ represents H, C1-C6 alkyl, or C6-C12 aryl;
• R represents H, alkali metal, C1-C6 alkyl, C6-C12 aryl or C(O)R′;
• and
• R′ represents H, C1-C20 alkyl or C6-C12 aryl,
• wherein the cyclodextrin encapsulates the pharmaceutical agent.