Scaffold for alloprosthetic composite implant
AssigneeMAKO Surgical Corp.
InventorPeter M. Bonutti
Life of this patent
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Abstract
An alloprosthetic composite implant comprising includes a structural porous scaffold having a pore density profile corresponding to a density profile of bone to be replaced. A plurality of cells are seeded within pores of the porous scaffold and grown by incubation. The cells may include osteoblasts and/or stem cells to form the structure of the implant, and one or more cartilage layers may be grown on top of the scaffold. The pore density profile of the scaffold may be formed based on one or both of the bone density profile of the bone to be removed, and the bone density profile of the native bone that will be in contact with the alloprosthetic implant. A robot may be employed reo resect the native bone and also to shape the alloprosthetic implant to fit into place in the native bone.
Claims20
An alloprosthetic composite implant for replacing a joint comprising:
- a structural porous scaffold having a pore density profile corresponding to a density profile of a bone of the joint to be replaced;
- a plurality of cells seeded within pores of the porous scaffold;
- and
- at least one layer of cartilage on an end of the scaffold, the cartilage adapted to replace at least a portion of a joint surface of the joint.
A method of implanting an alloprosthetic composite implant comprising:
- forming a scaffold having a pore density profile;
- seeding a plurality of viable cells into the scaffold;
- incubating the scaffold including the plurality of viable cells;
- robotically resecting native bone of a patient;
- robotically machining the alloprosthetic composite implant following incubation to have a shape corresponding to the native bone of the patient that is to be replaced.
Dependencies are inferred from the claim text.