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AssigneeRoche Diagnostics Operations, Inc.
InventorsHerbert Andres, Stefan Weiser, Johann Karl, Ursula Kunert, Florian Grupp
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The present invention relates to a method aiding in the assessment of rheumatoid arthritis (“RA”). The method is used in assessing RA in vitro. It is practiced by analyzing biochemical markers, comprising measuring the concentration of anti-CCP and anti-PIK3CD and correlating the concentrations determined to the absence or presence of RA. The invention also relates to the use of a marker panel comprising anti-CCP and anti-PIK3CD in the diagnosis of RA and it teaches a kit for performing the method of the invention. Further the invention relates to the use of a marker panel comprising anti-CCP and anti-PIK3CD to differentiate RA from other autoimmune diseases, preferably osteoarthritis (OA).
A method for assessing the absence or presence of rheumatoid arthritis (RA) in vitro by biochemical markers, comprising
A method for assessing a severity of rheumatoid arthritis (RA) in vitro by biochemical markers, comprising
A method for differentiation of rheumatoid arthritis (RA) from other autoimmune diseases in vitro by biochemical markers, comprising
A kit comprising reagents required to specifically measure anti-CCP and anti-PIK3CD, and optionally auxiliary reagents for performing the measurement.
Dependencies are inferred from the claim text.