Back to results
US 2018/0003611 A1Published application
Microfluidic Sensing
AssigneeHewlett-Packard Development Company, L.P.
InventorsJeremy Sells, Nick McGuinness, Chantelle Domingue, Manish Giri
Life of this patent
Estimating the term…
Abstract
A device including a microfluidic channel structure formed on a substrate and including a first channel and a fluid actuator within the microfluidic channel structure. A sense region within the first channel is to receive a fluid flow of target biologic particles for counting in a single file pattern, with the sense region having a volume on a same order of magnitude as a volume of a single one of the target biologic particles.
Claims15
A biologic test chip comprising:
- a substrate;
- a microfluidic channel structure formed on the substrate and including a first channel;
- a fluid actuator within the microfluidic channel structure.
- a sense region within the first channel to receive a fluid flow of biologic particles on a one-at-a-time basis via operation of the fluid actuator, the sense region having a volume on a same order of magnitude as a volume of a single respective one of the biologic particles.
1 more element
A biologic test chip comprising:
- a substrate;
- a microfluidic channel structure formed on the substrate and including:
- a first sensing portion including a first channel to receive a fluid including a first size biologic particles, the first channel including a first sense region having a first volume on a same order of magnitude as a volume of a single one of the first size biologic particles to cause single file counting at the first sense region;
- and
- a second sensing portion including a second channel to receive a fluid including a second size biologic particles, the second channel including a second sense region having a second volume on a same order of magnitude than a volume of a single one of the second size biologic particles to cause single file counting at the second sense region.
2 more elements
A kit comprising:
- a plurality of different biologic test chips with each chip corresponding to a differently-sized biologic particle, wherein each chip includes:
- a substrate;
- a microfluidic channel structure formed on the substrate and including a first channel;
- a fluid actuator within the microfluidic channel structure;
- and
- a sense region within the first channel to receive a single file fluid flow of biologic particles via operation of the fluid actuator, the sense region having a volume on a same order of magnitude as a volume of a single respective one of the biologic particles,
- wherein the sense volume of the sense region of a respective different chip corresponds a size of the biologic particle for that respective different chip.
4 more elements
Dependencies are inferred from the claim text.