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US 2018/0002661 A1Published application
Compositions of active wnt protein
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsRoeland Nusse, Karl H. Willert
Life of this patent
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Abstract
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
Claims18
1-12. (canceled)
An article of manufacture, comprising:
- a container;
- a label on the container;
- and
- a composition comprising a Wnt protein comprising a lipid moiety within the container.
1 more element
Dependencies are inferred from the claim text.