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US 2018/0002445 A1Published application
Antigen-binding constructs that bind to and inhibit catalase and/or superoxide dismutase as well as pharmaceutical compositions containing them for tumor therapy
OwnerGeorg BAUER, Manfred MOTZinventors
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Abstract
The invention relates to single domain VHH fragments which specifically bind to and inhibit superoxide dismutase and/or bind to and inhibit catalase and/or bind to and inhibit superoxide dismutase and catalase, in particular for the use in the therapy of tumor diseases.
Claims17
An antigen-binding construct that specifically binds to superoxide dismutase or catalase or both superoxide dismutase and catalase, characterized in that said construct is a single domain VHH fragment for use in the treatment of tumor diseases.
Dependencies are inferred from the claim text.