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US 2018/0002390 A1Published application
Compositions and methods for using actin-based peptides to modulate cellular bioactivity and cellular susceptibility to intracellular pathogens
OwnerYuntao Wuinventor
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Abstract
Compositions and methods for using actin-based peptides to modulate cellular bioactivity, including modulation of cellular susceptibility to intracellular pathogens, such as bacteria and viruses.
Claims21
An actin-based peptide, comprising
- an actin core domain and a cell penetration domain, operably linked together by a
- a spacer domain,
- wherein an N-terminus or C-terminus may have either the actin core domain or the cell penetration domain.
A method for controlling viral or bacterial infection, comprising
- administering an actin-based peptide to a cell, virus, or bacteria, in an amount sufficient to inhibit or enhance infection of said virus or bacteria.
(canceled)
A method for modulating cellular bioactivity, comprising:
- delivering into a cell one or more actin-based peptides selected from SEQ ID NOs:
- 1-845, in an amount effective to modulate cellular bioactivity.
Dependencies are inferred from the claim text.