Synthesis of heterocyclic compounds

A method for preparing a compound of formula (I):

• or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, said method comprising:
• contacting a compound of formula (Ia):
• with L2-P1 under conditions sufficient to form the compound of formula (I), wherein:
• Q is F or H;
• P2 is —C(O)—R3 or —C(O)—OR4;
• P1 is
• R1 is H or halogen;
• n is 0, 1 or 2;
• m is 1 or 2;
• R3 is C1-6alkyl, aryl, heteroaryl, aryl-C1-2alkyl, heteroaryl-C1-2alkyl, C3-10cycloalkyl, C3-10cycloalkyl-C1-2alkyl, ethynyl or vinyl, each of which is optionally substituted with 1-3 Ra groups;
• R4 is C1-6alkyl, aryl, heteroaryl, aryl-C1-2alkyl, heteroaryl-C1-2alkyl, C3-10cycloalkyl, C3-10cycloalkyl-C1-2alkyl, ethynyl or vinyl, each of which is optionally substituted with 1-3 Ra groups;
• L2 is Br, Cl, I, tosyl-O—, mesyl-O—, trifluoromethanesulfonyl-O—, —C(O)—O—CF3 or —C(O)—O—CH3;
• and
• each Ra group is independently halogen, C1-6alkyl, fluoro substituted C1-6alkyl, fluoro substituted C1-6alkoxy, aryl, heteroaryl, C1-6alkoxy, —CN, —NO2, —OH, —C(O)—O—C1-6alkyl, or —SiMe3, wherein the aliphatic or aromatic portion of Ra is further optionally substituted with from 1-3 Rb groups, wherein each Rb group is independently halogen, C1-6alkyl, C1-6alkoxy, —CN, —NO2 or —OH.